AOD-9604 vs HGH Fragment 176-191
A detailed side-by-side comparison of AOD-9604 and HGH Fragment 176-191 covering dosing, storage, research findings, and practical usage.
Overview
AOD-9604: A modified fragment of human growth hormone targeting fat metabolism.
HGH Fragment 176-191: The lipolytic fragment of human growth hormone (amino acids 176-191), targeting fat metabolism without the growth-promoting or diabetogenic effects of full-length HGH.
Comparison Table
| Property | AOD-9604 | HGH Fragment 176-191 |
|---|---|---|
| Category | Fat Loss | Fat Loss |
| Typical Dose | 250-500 mcg | 250-500 mcg |
| Frequency | 1x daily | 2x daily |
| Half-Life | ~30 minutes | ~30 minutes |
| Timing | Morning fasted | Morning fasted and before bed |
HGH Fragment 176-191 Research
HGH Fragment 176-191 is a synthetic peptide corresponding to the C-terminal portion (amino acids 176-191) of human growth hormone. Research published in journals including Endocrinology and Obesity Research has demonstrated that this specific fragment retains the lipolytic (fat-burning) activity of full-length HGH while lacking the growth-promoting and diabetogenic effects. In vitro studies show it stimulates lipolysis and inhibits lipogenesis in adipose tissue. Animal studies have demonstrated significant reductions in body fat without changes in IGF-1 levels, blood glucose, or insulin sensitivity — a key advantage over exogenous HGH. The fragment works by mimicking the way natural growth hormone regulates fat metabolism, specifically through beta-3 adrenergic receptor pathways. AOD-9604, a closely related peptide with an additional tyrosine residue, reached Phase 2b clinical trials for obesity. HGH Frag 176-191 remains an active area of research for targeted fat reduction without systemic growth hormone effects.
AOD-9604 Full Guide | HGH Fragment 176-191 Full Guide | Dosage Calculator | Browse Peptides
For laboratory research use only. Not for human consumption.