How Long Does Tesamorelin Last? Half-Life & Dosing Frequency
Tesamorelin has a reported half-life of 26-38 minutes. This page explains what that means for how long Tesamorelin stays active, how quickly it clears the body, and how often it is dosed in research.
What Is Tesamorelin's Half-Life?
The half-life of a compound is the time it takes for the amount in the body to fall to half its original level. For Tesamorelin, research reports a half-life of 26-38 minutes. A GHRH analog FDA-approved for reducing abdominal fat in HIV patients.
How Long Does Tesamorelin Stay in Your System?
A compound is generally considered mostly cleared after about five half-lives. With a half-life of 26-38 minutes, Tesamorelin is largely cleared after roughly 190 minutes. Individual metabolism, dose, and dosing frequency can shift this estimate.
What This Means for Dosing Frequency
Research protocols commonly use Tesamorelin 1x daily (Before bed or morning, fasted). Dosing frequency is generally matched to the half-life and to how long the compound's effects last — peptides with shorter half-lives are often dosed more frequently, while longer-acting compounds may be dosed less often.
Frequently Asked Questions
What is Tesamorelin's half-life?
In the research literature, Tesamorelin is reported to have a half-life of 26-38 minutes. Half-life is the time it takes for the amount of a compound in the body to fall to half of its original level.
How long does Tesamorelin stay in your system?
As a general pharmacokinetic rule, a compound is mostly cleared after about five half-lives. For Tesamorelin, with a half-life of 26-38 minutes, that works out to roughly 190 minutes. Individual metabolism, dose, and dosing frequency can shift this.
How often is Tesamorelin dosed?
Research protocols commonly use Tesamorelin 1x daily. Dosing frequency is generally matched to the compound's half-life and to how long its effects last.