Semax - Dosing Calculator & Information
Category: Nootropic & Cognitive
A synthetic peptide derived from ACTH with nootropic and neuroprotective effects.
Dosing Information
- Typical Dose Range: 200 - 1000 mcg
- Common Vial Sizes: 3mg
- Frequency: 1-2x daily
- Timing: Morning and early afternoon
Storage Guidelines
Before mixing: Room temperature up to 2 months, refrigerated (2-8°C) up to 18 months. Keep away from light and moisture. After mixing: Refrigerate at 2-8°C. Use within 2-3 weeks. Less stable than most peptides when reconstituted.
Frequently Asked Questions
How is Semax different from Selank?
Semax is more stimulating and cognitive-enhancing, while Selank is calming and anxiolytic. Semax boosts focus and energy; Selank reduces anxiety. They're often used together for balanced enhancement.
Can Semax cause anxiety?
Some users report mild stimulation or anxiety at higher doses. If this occurs, try reducing the dose or adding Selank to balance the stimulating effects.
How do I use Semax intranasally?
Reconstitute with bacteriostatic water, transfer to a nasal spray bottle, and administer 2-3 sprays per nostril. Use in morning/early afternoon - avoid evening dosing as it may affect sleep.
How long can I use Semax?
Semax doesn't appear to cause tolerance with regular use. Many users cycle it (e.g., 3 weeks on, 1 week off) though this isn't strictly necessary. Long-term daily use seems well-tolerated.
Research Summary
Semax is a synthetic heptapeptide derived from ACTH (adrenocorticotropic hormone), developed in Russia for cognitive enhancement and neurological conditions. Unlike ACTH, Semax has no hormonal activity and doesn't affect cortisol levels. Research has shown it increases BDNF (brain-derived neurotrophic factor), NGF (nerve growth factor), and enhances dopaminergic and serotonergic transmission. It's approved in Russia for stroke recovery, cognitive disorders, and optic nerve diseases. Users report improved focus, memory, mental clarity, and verbal fluency. Studies suggest neuroprotective properties and potential benefits for ADHD and depression.
Related Peptides
- Selank — A synthetic peptide derived from tuftsin with anxiolytic and nootropic properties.
- Dihexa — A potent nootropic peptide that enhances cognitive function and promotes neural connectivity.
- DSIP — A neuropeptide that promotes delta wave sleep and recovery.
Calculate Your Semax Dose
Use our free peptide calculator to get precise reconstitution volumes and injection dosages for Semax.