Semaglutide Reconstitution Calculator + Mixing Chart

Get exact reconstitution volumes and syringe units for Semaglutide.

Quick Answer

For a 3mg vial: add 0.6mL BAC water, draw 5 units for 250mcg.

Worked Example: 3mg Vial

  1. Vial contains 3,000 mcg (3mg x 1,000)
  2. Add 0.6mL water (60.00000000000001 units)
  3. Concentration = 50.0 mcg/unit
  4. Draw 5 units for 250mcg

Conversion Tables

3mg Vial + 0.6mL Water

DoseUnits
50mcg1 units
100mcg2 units
150mcg3 units
200mcg4 units
250mcg5 units
300mcg6 units
500mcg10 units
750mcg15 units
1mg20 units
1.5mg30 units
2mg40 units

5mg Vial + 1.0mL Water

DoseUnits
50mcg1 units
100mcg2 units
150mcg3 units
200mcg4 units
250mcg5 units
300mcg6 units
500mcg10 units
750mcg15 units
1mg20 units
1.5mg30 units
2mg40 units

10mg Vial + 2.0mL Water

DoseUnits
50mcg1 units
100mcg2 units
150mcg3 units
200mcg4 units
250mcg5 units
300mcg6 units
500mcg10 units
750mcg15 units
1mg20 units
1.5mg30 units
2mg40 units

About Semaglutide

Semaglutide is an FDA-approved GLP-1 receptor agonist originally developed for Type 2 diabetes (Ozempic) and later approved for chronic weight management (Wegovy). It mimics the hormone GLP-1, which regulates appetite, food intake, and blood sugar levels. Clinical trials have demonstrated impressive weight loss results, with participants losing an average of 15-17% of body weight over 68 weeks. Semaglutide works by slowing gastric emptying, reducing appetite, and improving insulin sensitivity. It also shows cardiovascular benefits, reducing major adverse cardiac events in at-risk patients. The once-weekly dosing makes it convenient compared to daily alternatives.

FAQ

How much weight can I lose on semaglutide?

Clinical trials show average weight loss of 15-17% of body weight over 68 weeks at full dose. Individual results vary based on diet, exercise, and starting weight. Some lose more, some less.

Why do I need to titrate up slowly?

Slow titration (starting at 0.25mg and increasing monthly) helps your body adjust and minimizes side effects like nausea, vomiting, and diarrhea. Rushing the dose often leads to severe GI symptoms.

What are common semaglutide side effects?

The most common side effects are gastrointestinal: nausea, vomiting, diarrhea, constipation, and stomach pain. These usually improve over time. More serious but rare effects include pancreatitis and gallbladder issues.

Semaglutide vs Tirzepatide - which is better?

Tirzepatide (Mounjaro/Zepbound) has shown slightly better weight loss results in trials (up to 22% vs 17%). However, semaglutide has more long-term safety data. Both are effective - choice often depends on availability and cost.

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